Chapter

Genetic Association Studies

Ezra Susser, Sharon Schwartz, Alfredo Morabia and Evelyn J. Bromet

in Psychiatric Epidemiology

Published in print July 2006 | ISBN: 9780195101812
Published online September 2009 | e-ISBN: 9780199864096 | DOI: http://dx.doi.org/10.1093/acprof:oso/9780195101812.003.29

Series: Oxford Psychiatry Series

Genetic Association Studies

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This chapter focuses on genetic association studies. The goal of genetic association studies is to investigate the effects of genotypic variation on disease risk. These designs are built on a concept of a genetic cause that closely resembles the concept of a risk factor in epidemiology. Moreover, they correspond well to designs previously articulated by risk factor epidemiologists. Thus, the concepts and methods of risk factor epidemiology are particularly useful in this context.

Keywords: cohort study; genetic association study; case-control design; family-based design; case-parent triad design

Chapter.  9488 words.  Illustrated.

Subjects: Public Health and Epidemiology

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