Chapter

Modern Family History Studies

Ezra Susser, Sharon Schwartz, Alfredo Morabia and Evelyn J. Bromet

in Psychiatric Epidemiology

Published in print July 2006 | ISBN: 9780195101812
Published online September 2009 | e-ISBN: 9780199864096 | DOI: http://dx.doi.org/10.1093/acprof:oso/9780195101812.003.30

Series: Oxford Psychiatry Series

Modern Family History Studies

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Family history studies are now used for a much wider range of purposes than in the past. This chapter discusses their usefulness for refining phenotype definitions, targeting preventive interventions, characterizing genetic effects, and exploring gene-environment interaction. These are in addition to their original role in genetic research, which was to examine whether diseases aggregate in families. The chapter also elaborates on their relationship to the risk factor designs described in previous chapters.

Keywords: family history study; genetic research; risk factor; phenotype definitions; preventive interventions; genetic effects; gene-environment interaction

Chapter.  6069 words.  Illustrated.

Subjects: Public Health and Epidemiology

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