Chapter

Glucagon and the Control of Meal Size

NORI GEARY

in Satiation: From Gut to Brain

Published in print January 1998 | ISBN: 9780195105155
Published online March 2012 | e-ISBN: 9780199848263 | DOI: http://dx.doi.org/10.1093/acprof:oso/9780195105155.003.0007
Glucagon and the Control of Meal Size

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This chapter evaluates the satiating effect of pancreatic glucagon. Two studies were published in 1977 and the results of these studies suggested that exogenous glucagon can pharmacologically increase satiety in rats. Several other studies have confirmed the presence of prandial glucagon secretion during mixed nutrient meals in humans. The existence of prandial glucagon secretion suggests the hypothesis that endogenous glucagon is a signal for terminating a meal.

Keywords: pancreatic glucagon; exogenous glucagon; satiety; prandial glucagon; endogenous glucagon

Chapter.  12973 words.  Illustrated.

Subjects: Neuroscience

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