Chapter

Molecular mechanisms of axon guidance and target recognition

Corey S. Goodman and Marc Tessier-Lavigne

in Molecular and Cellular Approaches to Neural Development

Published in print April 1998 | ISBN: 9780195111668
Published online May 2009 | e-ISBN: 9780199865833 | DOI: http://dx.doi.org/10.1093/acprof:oso/9780195111668.003.0004
 Molecular mechanisms of axon guidance and target recognition

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This chapter discusses the molecular mechanisms that direct the initial migration of axons and establish the initial stereotyped patterns of projections and connections. It begins with a review of the cellular mechanisms that direct growing axons. It then presents an overview of the families of guidance molecules and receptors involved in this process. Finally, the chapter discusses the specific guidance events in which the precise guidance roles of different molecules have been defined through experimental analysis.

Keywords: axons; projections; connections; cellular mechanisms; guidance molecules; receptors

Chapter.  34868 words.  Illustrated.

Subjects: Neuroscience

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