Diet and Coronary Heart Disease

Walter Willett

in Nutritional Epidemiology

Second edition

Published in print July 1998 | ISBN: 9780195122978
Published online September 2009 | e-ISBN: 9780199864249 | DOI:

Series: Monographs in Epidemiology and Biostatistics

Diet and Coronary Heart Disease

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According to the classic “diet-heart” hypothesis, high intake of saturated fats and cholesterol and low intake of polyunsaturated fats increase the level of serum cholesterol, which leads to the development of atheromatous plaques. Accumulation of plaque narrows the coronary arteries, reduces blood flow to the heart muscle, finally leading to myocardial infarction. This chapter examines the epidemiologic evidence addressing this hypothesis and considers additional hypotheses relating to diet and heart disease.

Keywords: diet; heart disease; nutritional epidemiology; epidemiologic studies; atheromatous plagues

Chapter.  31617 words.  Illustrated.

Subjects: Public Health and Epidemiology

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