Analysis of Matched Studies

Theodore R. Holford

in Multivariate Methods in Epidemiology

Published in print July 2002 | ISBN: 9780195124408
Published online September 2009 | e-ISBN: 9780199864270 | DOI:

Series: Monographs in Epidemiology and Biostatistics

Analysis of Matched Studies

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This chapter discusses methods of analysis for studies that employed matching in order to adjust for potential confounding of the disease exposure association of interest. It distinguishes between a general strategy of stratification to achieve balance for an important covariate, which can subsequently be included in the analysis; and rigorous matching in which one or two unique controls are identified for a study subject. The first methods considered made use of score statistics. These methods were then extended to model fitting, which can be accomplished using either logistic regression or proportional hazards software. Exercises are provided at the end of the chapter.

Keywords: matching strategy; matched pairs; case control studies; cohort studies

Chapter.  9231 words.  Illustrated.

Subjects: Public Health and Epidemiology

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