Chapter

The Role of Epidemiology in Estimating Radiation Risk: Basic Methods and Applications

Owen J. Devine and Paul L. Garbe

in Radiological Risk Assessment and Environmental Analysis

Published in print July 2008 | ISBN: 9780195127270
Published online September 2008 | e-ISBN: 9780199869121 | DOI: http://dx.doi.org/10.1093/acprof:oso/9780195127270.003.0013
 						The Role of Epidemiology in Estimating Radiation Risk: Basic Methods and Applications

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This chapter provides an overview of methods used in epidemiologic investigations with a special emphasis on approaches pertinent to radiation-related epidemiology. It begins with a description of how the risk and rate of disease are estimated on the basis of observed disease counts. The discussion continues by examining measures of association used to evaluate potential relationships between these risk and rate estimates and exposure to a suspected causative factor. In addition, a discussion is provided on methods for evaluating the magnitude of an observed association between disease risk and exposure in light of the random variation expected in observable measures of disease burden. The chapter concludes with an examination of issues specifically related to epidemiologic investigations of exposures to radioactive materials, including the critical nature of appropriate dosimetric practice.

Keywords: radiation risk; disease burden; risk measures; disease rates; risk estimates

Chapter.  19496 words.  Illustrated.

Subjects: Animal Pathology and Diseases

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