Chapter

Public health assessment of genetic susceptibility to infectious diseases: malaria, tuberculosis, and HIV

Janet M McNicholl, Marie V. Downer, Michael Aidoo, Thomas Hodge and Venkatachalam Udhayakumar

in Genetics and Public Health in the 21st Century

Published in print September 2000 | ISBN: 9780195128307
Published online September 2009 | e-ISBN: 9780199864485 | DOI: http://dx.doi.org/10.1093/acprof:oso/9780195128307.003.0010

Series: Oxford Monographs on Medical Genetics

Public health assessment of genetic susceptibility to infectious diseases: malaria, tuberculosis, and HIV

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The understanding of the host genetic factors that influence susceptibility to and the course of infectious diseases is growing rapidly. Even for the most common pathogens, however, there is an incomplete understanding of all the important genes. As sequencing of the more than 100,000 human genes continues and as technologies advance, new discoveries about host genes and their role in infectious diseases are made almost daily. Translating this knowledge into public health actions, particularly those aimed at combating and controlling infectious diseases, is a major challenge. This chapter focuses on this downstream phase of genetics, particularly on how new knowledge can be integrated into existing public health programs and strategies.

Keywords: public health; genetic factors; infectious disease; genetics; disease prevention; malaria; tuberculosis; HIV/AIDS

Chapter.  11873 words. 

Subjects: Public Health and Epidemiology

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