Fatigue in Medical Illness: Research Issues

Russell K. Portenoy and Eduardo Bruera

in Issues in Palliative Care Research

Published in print September 2003 | ISBN: 9780195130652
Published online November 2011 | e-ISBN: 9780199999842 | DOI:
Fatigue in Medical Illness: Research Issues

Show Summary Details


Fatigue is a highly prevalent and complex symptom in populations with chronic illness. Although there have been significant advances in the methodologies to measure fatigue, few scientific investigations have focused on the nature of the problem and its management in clinical settings. In many ways, fatigue research is now at a point similar to pain research a quarter-century ago. Valid and reliable measurement is possible, and a growing number of epidemiological studies have established the seriousness of the clinical problem. The field is primed for studies that may illuminate the pathophysiology of the disorder in varied patient populations and provide an evidence base for treatment selection. However, studies are needed to clarify the mechanisms that underlie various types of fatigue, understand the epidemiology of the symptom, and provide an evidence base for management decisions.

Keywords: fatigue assessment; chronic illness; pain research; pathophysiology

Chapter.  8712 words. 

Subjects: Palliative Medicine

Full text: subscription required

How to subscribe Recommend to my Librarian

Buy this work at Oxford University Press »

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.