Chapter

Functional Architecture of the Dorsolateral Prefrontal Cortex in Monkeys and Humans

Patricia S. Goldman-Rakic and Hoi-Chung Leung

in Principles of Frontal Lobe Function

Published in print August 2002 | ISBN: 9780195134971
Published online May 2009 | e-ISBN: 9780199864157 | DOI: http://dx.doi.org/10.1093/acprof:oso/9780195134971.003.0005
Functional Architecture of the Dorsolateral Prefrontal Cortex in Monkeys and Humans

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This chapter argues that findings from neurophysiology, neuroanatomy, and functional magnetic resonance imaging (fMRI) are essential for a comprehensive understanding of the structure of executive processes. In particular, the dorsolateral prefrontal cortex in the nonhuman primate can serve as an unparalleled model system for studying visual memory and examining its properties. Analysis of one system in detail will help to address the larger issues of domain specificity, the neural basis of storage and processing functions, and plasticity within working memory.

Keywords: working memory; executive processes; nonhuman primates; fMRI; dorsolaterla prefrontal cortex

Chapter.  5991 words.  Illustrated.

Subjects: Neuroscience

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