Chapter

The Role of Prefrontal Cortex in Normal and Disordered Cognitive Control: A Cognitive Neuroscience Perspective

Todd S. Braver, Jonathan D. Cohen and Deanna M. Barch

in Principles of Frontal Lobe Function

Published in print August 2002 | ISBN: 9780195134971
Published online May 2009 | e-ISBN: 9780199864157 | DOI: http://dx.doi.org/10.1093/acprof:oso/9780195134971.003.0027
The Role of Prefrontal Cortex in Normal and Disordered Cognitive Control: A Cognitive Neuroscience Perspective

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This chapter presents a theory of prefrontal cortex (PFC) function using the connectionist computational modeling framework. This modeling approach involves three components: (1) computational analysis of the critical processing mechanisms required for cognitive control; (2) use of neurobiologically plausible principles of information processing; and (3) implementation and simulation of cognitive tasks and behavioral performance. The chapter describes behavioral and neuroimaging data on healthy young adults that validate critical components of the model. It then summarizes the application of the model to the clinical domain. These studies highlight the power of the cognitive neuroscience approach by demonstrating how a single, integrated account of PFC function can capture a wide range of data from different methodologies and multiple populations.

Keywords: prefrontal cortex function; computational modeling; cognitive control; PFC; computational analysis

Chapter.  11683 words.  Illustrated.

Subjects: Neuroscience

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