Chapter

Normal Development of Prefrontal Cortex from Birth to Young Adulthood: Cognitive Functions, Anatomy, and Biochemistry

Adele Diamond

in Principles of Frontal Lobe Function

Published in print August 2002 | ISBN: 9780195134971
Published online May 2009 | e-ISBN: 9780199864157 | DOI: http://dx.doi.org/10.1093/acprof:oso/9780195134971.003.0029
Normal Development of Prefrontal Cortex from Birth to Young Adulthood: Cognitive Functions, Anatomy, and Biochemistry

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The prefrontal cortex (PFC) undergoes one of the longest periods of development of any brain region, taking over two decades to reach full maturity in humans. This chapter focuses on normal development, dividing it into the following epochs: 0-1 years, 1-3 years, 3-7 years, and 7 years through early adulthood. For each epoch, it summarizes some of what is known about (a) the development of the working memory and inhibitory control functions that depend on PFC and (b) the anatomical and biochemical developmental changes in PFC during that period.

Keywords: brain development; working memory; inhibitory control functions; prefrontal cortex

Chapter.  22360 words.  Illustrated.

Subjects: Neuroscience

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