Chapter

Characterizing Receptors (1905–1983)

Joseph D. Robinson

in Mechanisms of Synaptic Transmission

Published in print June 2001 | ISBN: 9780195137613
Published online March 2012 | e-ISBN: 9780199848164 | DOI: http://dx.doi.org/10.1093/acprof:oso/9780195137613.003.0006
Characterizing Receptors (1905–1983)

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In 1905, John Newport Langley introduced the notion that nerve activity, excitatory drugs, and their antagonists all elicited cellular responses through “receptive substances,” hypothetical structures that soon became known as receptors. This chapter describes attempts to answer essential questions raised by Langley's proposal: what, chemically, are these receptors; how do neurotransmitters and drugs interact with them; and how do such interactions trigger the cellular responses?

Keywords: Langley; receptors; neurotransmitters; drugs; cellular responses

Chapter.  10145 words.  Illustrated.

Subjects: Neuroscience

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