Chapter

Receptor Structures and Receptor Families(1983–1990)

Joseph D. Robinson

in Mechanisms of Synaptic Transmission

Published in print June 2001 | ISBN: 9780195137613
Published online March 2012 | e-ISBN: 9780199848164 | DOI: http://dx.doi.org/10.1093/acprof:oso/9780195137613.003.0008
Receptor Structures and Receptor Families(1983–1990)

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This chapter discusses two major classes of receptor function and structure: oligomeric subunits surrounding an ion-conducting pore formed a ligand-gated ion channel that opened when neurotransmitters filled the binding sites and monomeric proteins with seven transmembrane segments formed receptors that activated a coupled G-protein. With the first class, chemical signals or neurotransmitters were converted into electrical signals. With the second, chemical signals were converted to different chemical signals: G-proteins that then interacted with various enzymes and channels to elicit both chemical and electrical responses.

Keywords: receptor; oligomeric subunits; monomeric protein; chemical signals; neurotransmitters; electrical signals

Chapter.  7666 words.  Illustrated.

Subjects: Neuroscience

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