Chapter

<i>Exploring Declarative Memory Using Animal Models</i>

Howard Eichenbaum

in The Cognitive Neuroscience of Memory

Published in print March 2002 | ISBN: 9780195141740
Published online May 2009 | e-ISBN: 9780199865741 | DOI: http://dx.doi.org/10.1093/acprof:oso/9780195141740.003.0005
 Exploring Declarative Memory Using Animal Models

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This chapter discusses research in the development of animal models for amnesia. Studies provide compelling evidence for a comprehensive account of the cognitive mechanisms of declarative memory. Various kinds of learning, spatial and nonspatial, simple and complex, can be accomplished independent of the hippocampus in animals, as indeed is the case in human amnesic patients as well. However, the hippocampus is required to link together the representations of overlapping experiences into a relational representation, and supports the flexible and inferential expression of indirect associations among items within the larger organization of linked memories.

Keywords: amnesia; experimental models; memory; hippocampus

Chapter.  12365 words.  Illustrated.

Subjects: Neuroscience

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