Chapter

Matched Analysis (One Case and Two Controls)

Steve Selvin

in Epidemiologic Analysis

Published in print August 2001 | ISBN: 9780195146189
Published online September 2009 | e-ISBN: 9780199864720 | DOI: http://dx.doi.org/10.1093/acprof:oso/9780195146189.003.0008
Matched Analysis (One Case and Two Controls)

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This chapter examined whether exposure to electromagnetic radiation is associated with the risk of a birth defect. More specifically, does a newborn infant whose mother lives near high-voltage power lines have an increased risk of a congenital anomaly? Two definitions of exposure show no important association between the proximity to high-power lines (emf) and the risk of a birth defect among newborn infants. Matched analyses using the directly observed distance show a slight but not significantly smaller distance to power lines among the cases compared to controls. A Mest, a bootstrap analysis, and an analysis of variance provide little evidence that this association is not entirely due to random variation. Defining risk as a binary variable, matched analyses again provide little evidence of an association.

Keywords: electromagnetic radiation; birth defects; power lines; congenital defect

Chapter.  5392 words.  Illustrated.

Subjects: Public Health and Epidemiology

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