Chapter

Immunologic Factors

GARETH J. MORGAN, MARTHA S. LINET and CHARLES S. RABKIN

in Cancer Epidemiology and Prevention

Third edition

Published in print October 2006 | ISBN: 9780195149616
Published online September 2009 | e-ISBN: 9780199865062 | DOI: http://dx.doi.org/10.1093/acprof:oso/9780195149616.003.0027
Immunologic Factors

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This chapter discusses the immunologic factors in cancer. Topics covered include structure and function of the immune system, immune variation and cancer risk, and age-related changes in immune function. Experience with a wide range of immune deficient conditions indicates that loss of immune competence does not globally increase cancer incidence. Limited sets of malignancies are increased that are specific to the underlying immune abnormalities. A common feature is the prominent excess of non-Hodgkin lymphoma (NHL) in many of these disorders.

Keywords: cancer risk; immune system; immune function; non-Hodgkin lymphoma

Chapter.  15406 words.  Illustrated.

Subjects: Public Health and Epidemiology

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