Chapter

Genetic Modifiers of Cancer Risk

NEIL E. CAPORASO

in Cancer Epidemiology and Prevention

Third edition

Published in print October 2006 | ISBN: 9780195149616
Published online September 2009 | e-ISBN: 9780199865062 | DOI: http://dx.doi.org/10.1093/acprof:oso/9780195149616.003.0029
Genetic Modifiers of Cancer Risk

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This chapter discusses genetic modifiers of cancer risk. Topics covered include rationale for the study of low-penetrance genes, the role of low-penetrance genes in cancer susceptibility, methodological issues, gene selection in population studies, overview of candidate genes, overview of cancer-specific associations, and gene-environment interaction.

Keywords: cancer susceptibility; low-penetrance genes; gene selection; candidate genes; gene-environment interaction

Chapter.  25699 words. 

Subjects: Public Health and Epidemiology

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