Chapter

Radial Glial Cells: Scaffolding for Cortical Development and Evolution

Pasko Rakic

in Neuroglia

Published on behalf of Oxford University Press

Published in print October 2004 | ISBN: 9780195152227
Published online September 2013 | e-ISBN: 9780199865024 | DOI: http://dx.doi.org/10.1093/acprof:oso/9780195152227.003.0031
                      Radial Glial Cells: Scaffolding for Cortical Development and Evolution

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Radial glial cells derive from the neuroepithelial cells during restricted developmental periods in most regions of the vertebrate brain. The diversity of functions and the variety of morphogenetic transformations observed in different regions and species suggest that this cell class has played a pivotal role in the expansion of the cerebral cortex during evolution. This chapter focuses on the radial and Bergmann glial cells and their role in the developing mammalian cortical structures, with particular emphasis on the cerebral and cerebellar cortex in the large primate brain.

Keywords: Bergmann glial cells; cerebral cortex; cerebellar cortex; primate brain; evolution

Chapter.  11567 words.  Illustrated.

Subjects: Neuroscience

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