Chapter

Astrocytic Swelling in Neuropathology

Alexander A. Mongin and Harold K. Kimelberg

in Neuroglia

Published on behalf of Oxford University Press

Published in print October 2004 | ISBN: 9780195152227
Published online September 2013 | e-ISBN: 9780199865024 | DOI: http://dx.doi.org/10.1093/acprof:oso/9780195152227.003.0044
                      Astrocytic Swelling in Neuropathology

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Brain edema is a dangerous and frequently life-threatening neurological complication. Unlike other tissues, the brain is encased within a rigid skull, and even small increases in tissue volume produce significant rises in intracranial pressure, causing compression of neural tissue and blood vessels leading to brain tissue damage mostly due to blood flow reduction. Brain edema can be broadly classified into two categories: vasogenic edema and cytotoxic (or cellular) edema. This chapter focuses on cellular edema, its molecular mechanisms, and potential significance in several major neurological disorders.

Keywords: brain edema; brain swelling; cellular edema; astrocyte

Chapter.  9516 words.  Illustrated.

Subjects: Neuroscience

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