Chapter

Prokaryotes Take Center Stage

Rowland H. Davis

in The Microbial Models of Molecular Biology

Published in print September 2003 | ISBN: 9780195154368
Published online April 2010 | e-ISBN: 9780199893935 | DOI: http://dx.doi.org/10.1093/acprof:oso/9780195154368.003.0011
Prokaryotes Take Center Stage

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The previous 50 years had been devoted in large part to discovering the nature of the gene through studies of its function, mutation, and recombination. What was there for geneticists to learn after Watson and Crick's famous discovery? The answer lies in the transformation of genetics from its preoccupation with the identity of the gene to the use of genetics as an analytical tool. Genetic rationales would probe the properties of DNA in the living system and would continue to extend themselves into the analysis of many complex structures and processes. Genetics began to lose its identity as a separate field as it invaded almost every area of biological science. This chapter explores the major trends of investigation with prokaryotes mainly in the years 1953-65, focusing on the use of model organisms that have been considered so far in particular programs.

Keywords: prokaryotes; model organisms; model systems; E. coli; bacterial genetics

Chapter.  11305 words.  Illustrated.

Subjects: Biochemistry

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