Rowland H. Davis

in The Microbial Models of Molecular Biology

Published in print September 2003 | ISBN: 9780195154368
Published online April 2010 | e-ISBN: 9780199893935 | DOI:

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After the genetic code had been defined fully (by 1963), some believed that it was all over. This feeling signified only that the goals of many up to that time had been so narrowly conceived that their attainment left nothing to aim for. For those who thought this way, continued study of these phenomena would consign them to gleaning the stubble of a freshly harvested terrain; the clean-up job of ordinary, journeyman scientists. For others, the Central Dogma and the explication of the genetic code were simply open doors to the real, newly appreciated, unique biochemical mechanisms of protein and nucleic acid synthesis, the broad, formal outline of these life processes now behind them. For others, observation and imagination would define problems previously undreamt of. Fortunately, tastes vary, and work continued in earnest, in many ways and on many fronts. This chapter considers the sweeping developments after 1963.

Keywords: prokaryotes; model organisms; model systems; E. coli; bacterial genetics; DNA

Chapter.  4879 words. 

Subjects: Biochemistry

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