This chapter reviews functional neuroimaging studies of memory in young adults, older adults, and patients with dementia that have used the traditional univariate subtraction approach. It shows how examination of functional connectivity can be useful in identifying between-group differences not possible with univariate approaches. It focuses on changes involving prefrontal cortex and the hippocampus because these areas are thought by some to be particularly vulnerable to aging, and much of the neuroimaging literature on memory has focused on these regions.
Keywords: functional neuroimaging dementia; memory; univariate subtraction approach; prefrontal cortex; hippocampus; aging; young adults; older adults
Chapter. 11538 words. Illustrated.
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