Sex and Drugs

Susan C. Han and Suzette M. Evans

in Mind-Altering Drugs

Published in print May 2005 | ISBN: 9780195165319
Published online April 2010 | e-ISBN: 9780199894055 | DOI:
Sex and Drugs

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This chapter reviews studies of sex differences in drug abuse. There is increasing preclinical and clinical evidence that gonadal hormones play a role in the subjective effects, reinforcing effects, and other effects of abused drugs. Despite this growing evidence, most studies that include women ignore the menstrual cycle. Until more studies are conducted to provide sufficient evidence that the subjective effects of a particular drug do not vary across the menstrual cycle, studies comparing males and females need to control for menstrual cycle phase in a systematic fashion.

Keywords: drug use; drug abuse; sex differences; menstrual cycle; women; subjective effects

Chapter.  14852 words. 

Subjects: Clinical Pharmacology and Therapeutics

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