Subjective Effects of Opioids

Sandy M. Comer and James P. Zacny

in Mind-Altering Drugs

Published in print May 2005 | ISBN: 9780195165319
Published online April 2010 | e-ISBN: 9780199894055 | DOI:
Subjective Effects of Opioids

More Like This

Show all results sharing this subject:

  • Clinical Pharmacology and Therapeutics


Show Summary Details


Opioids, which have long been abused, are capable of producing euphoria and other “positive” subjective effects. Although the relationship between positive subjective effects and abuse of a drug is not necessarily causal, there is a predictive relationship between those drugs that produce a positive spectrum of subjective effects and their likelihood of functioning as reinforcers and being abused. A host of factors influence the subjective effects of opioids (and subsequently their abuse liability); some of the more salient ones are covered in this chapter. It first describes how subjective effects of opioids are measured and then discusses how such factors as dose, route of administration, rate of onset of drug effects, tolerance and dependence, and drug use history can all influence an opioid's subjective effects.

Keywords: opioids; drug abuse; subjective effects; drug use

Chapter.  10020 words. 

Subjects: Clinical Pharmacology and Therapeutics

Full text: subscription required

How to subscribe Recommend to my Librarian

Buy this work at Oxford University Press »

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.