Chapter

Neuroplasticity and Aggression: An Interaction Between Vasopressin and Serotonin

Craig F. Ferris

in Biology of Aggression

Published in print September 2005 | ISBN: 9780195168761
Published online May 2009 | e-ISBN: 9780199865444 | DOI: http://dx.doi.org/10.1093/acprof:oso/9780195168761.003.0007
 							Neuroplasticity and Aggression: An Interaction Between Vasopressin and Serotonin

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This chapter focuses on two neurochemical signals that control aggression—serotonin (5-hydroxytryptamine, or 5-HT) and vasopressin (VP). 5-HT and VP appear to play significant roles in the regulation of impulsivity and aggression. 5-HT reduces aggressive responding, while VP enhances arousal and aggression in a context-dependent manner. The interaction between the brain and the environment is regulated, in part, by changes in gonadal and adrenal steroids. The stress of social subjugation alters the levels of testosterone and stress hormones, affecting gene transcription and translation. The VP/5-HT systems are sensitive to changes in these steroid hormones linking the neurochemical regulation of aggression to environmental events.

Keywords: aggressive behavior; neurochemical signals; 5-hydroxytryptamine; glucocorticoids; testosterone. environment

Chapter.  9168 words. 

Subjects: Neuroscience

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