Chapter

The Role of Estrogen Receptors in the Regulation of Aggressive Behaviors

Sonoko Ogawa, Masayoshi Nomura, Elena Choleris and Donald Pfaff

in Biology of Aggression

Published in print September 2005 | ISBN: 9780195168761
Published online May 2009 | e-ISBN: 9780199865444 | DOI: http://dx.doi.org/10.1093/acprof:oso/9780195168761.003.0010
 							The Role of Estrogen Receptors in the Regulation of Aggressive Behaviors

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At least two types of estrogen receptors (ERs), the classical ER-α and the more recently identified ER-β, have been localized in the central nervous system. ER-α and ER-β are very similar estrogen binding proteins that act as ligand-dependent transcription factors. Although somewhat overlapping, brain distributions of ER-α and ER-β are not identical. This chapter summarizes current knowledge of the possible differential roles played by the two types of ERs in the expression of aggressive behavior. It also discusses potential brain mechanisms of ER-mediated regulation of aggression.

Keywords: aggression; mice; male aggressive behavior; female aggressive behavior

Chapter.  11697 words.  Illustrated.

Subjects: Neuroscience

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