Chapter

Dopamine’s Influence on Prefrontal Cortical Cognition: Actions and Circuits in Behaving Primates

Amy F.T. Arnsten, Susheel Vijayraghavan, Min Wang, Nao J. Gamo and Constantinos D. Paspalas

in Dopamine Handbook

Published in print October 2009 | ISBN: 9780195373035
Published online February 2010 | e-ISBN: 9780199865543 | DOI: http://dx.doi.org/10.1093/acprof:oso/9780195373035.003.0016
Dopamine’s Influence on Prefrontal Cortical Cognition: Actions and Circuits in Behaving Primates

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This chapter summarizes current knowledge of dopamine (DA) and DA receptor localization in primate prefrontal cortex (PFC), and the powerful influences of DA on PFC physiology and cognitive function. It begins with an overview of PFC function, physiology, and circuitry. It then discusses the anatomy of DA and its receptors in the primate PFC, the effects of DA on PFC physiology and function, and the role of changes in DA transmission in PFC in several neuropsychiatric disorders.

Keywords: dopamine; prefrontal cortex; primates; cognitive function; neuropsychiatric disorders

Chapter.  12519 words.  Illustrated.

Subjects: Neuroscience

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