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Conditioned Taste Aversion

Jan Bures, F. Bermudez-Rattoni and T. Yamamoto

Published in print May 1998 | ISBN: 9780198523475
Published online January 2008 | e-ISBN: 9780191712678 | DOI: http://dx.doi.org/10.1093/acprof:oso/9780198523475.001.0001

Series: Oxford Psychology Series

Conditioned Taste Aversion

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Conditioned taste aversion (CTA) is a robust defence device protecting animals against the repeated consumption of toxic food. CTA is due to an association of the gustatory conditional stimulus (CS) with the delayed visceral unconditional stimulus (US). Chapter 1 gives a brief survey of the history of CTA. Chapter 2 describes the methodology of behavioral tests undertaken. Chapter 3 reviews the centers in the brainstem, the diencephalon and insular cortex: the removal of which interferes with CTA. Chapter 4 deals with CTA disruption by local inactivation of insular cortex and of various extracortical regions. Chapter 5 describes drugs which can serve as US in CTA experiments or can block CTA retrieval. Chapter 6 describes the electrophysiology of neurons during formation or retrieval of CTA. Chapter 7 analyzes the interaction of gustatory and visceral afferents manifested by c-fos early genes. Chapter 8 concentrates on the possible repair of CTA blocking lesions by transplantation of fetal grafts. Chapter 9 discusses the paradoxes of CTA research, e.g., learning without awareness, CTA formed during blockade of proteosynthesis, or by rewarding drugs.

Keywords: malaise; history of CTA; behavioral tests; brainstem; diencephalon; insular cortex; drugs; electrophysiology; c-fos early genes; fetal grafts

Book.  192 pages.  Illustrated.

Subjects: Neuropsychology

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Table of Contents

Neuroanatomy of CTA: lesion studies in Conditioned Taste Aversion

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Functional ablation studies of CTA in Conditioned Taste Aversion

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Pharmacology of CTA in Conditioned Taste Aversion

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Electrophysiology of CTA in Conditioned Taste Aversion

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Functional morphology of CTA in Conditioned Taste Aversion

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Transplantation studies in Conditioned Taste Aversion

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