Chapter

Lipids and cholesterol

M. R. Law and A. Rodgers

in Coronary Heart Disease Epidemiology

Second edition

Published in print June 2005 | ISBN: 9780198525738
Published online September 2009 | e-ISBN: 9780191724114 | DOI: https://dx.doi.org/10.1093/acprof:oso/9780198525738.003.0012
Lipids and cholesterol

Show Summary Details

Preview

This chapter discusses the role of lipids and cholesterol in coronary heart disease (CHD). The high levels of serum cholesterol found in Western populations are a major cause of the high mortality from CHD. Realistic dietary change in a community can lower serum cholesterol by 0.6 mmol/l (10%) and reduce heart disease mortality by approximately 25% among middle-aged individuals. Cholesterol-lowering drugs (statins) can lower cholesterol by 1.8 mmol/l (30%), and reduce the risk of heart disease death by approximately 60% from the third year onwards. Statins are inexpensive and safe, and their widespread use should be encouraged.

Keywords: coronary heart disease; cholesterol-lowering drugs; low-density lipoprotein; high-density lipoprotein; diet; statins

Chapter.  6301 words.  Illustrated.

Subjects: Public Health and Epidemiology

Full text: subscription required

How to subscribe Recommend to my Librarian

Buy this work at Oxford University Press »

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.