Lipids and cholesterol

M. R. Law and A. Rodgers

in Coronary Heart Disease Epidemiology

Second edition

Published in print June 2005 | ISBN: 9780198525738
Published online September 2009 | e-ISBN: 9780191724114 | DOI:
Lipids and cholesterol

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This chapter discusses the role of lipids and cholesterol in coronary heart disease (CHD). The high levels of serum cholesterol found in Western populations are a major cause of the high mortality from CHD. Realistic dietary change in a community can lower serum cholesterol by 0.6 mmol/l (10%) and reduce heart disease mortality by approximately 25% among middle-aged individuals. Cholesterol-lowering drugs (statins) can lower cholesterol by 1.8 mmol/l (30%), and reduce the risk of heart disease death by approximately 60% from the third year onwards. Statins are inexpensive and safe, and their widespread use should be encouraged.

Keywords: coronary heart disease; cholesterol-lowering drugs; low-density lipoprotein; high-density lipoprotein; diet; statins

Chapter.  6301 words.  Illustrated.

Subjects: Public Health and Epidemiology

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