Chapter

Protecting human subjects in brain research: a pragmatic perspective

Franklin G. Miller and Joseph J. Fins

in Neuroethics

Second edition

Published in print April 2004 | ISBN: 9780198567219
Published online September 2009 | e-ISBN: 9780191724084 | DOI: http://dx.doi.org/10.1093/acprof:oso/9780198567219.003.0009
Protecting human subjects in brain research: a pragmatic perspective

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This chapter elucidates ethical considerations in designing and carrying out clinical research on people with brain disorders based on an approach to research ethics derived from American philosophical pragmatism. Focusing on placebo-controlled trials of pharmacological treatments and deep-brain stimulation for psychiatric and neurological disorders, the chapter reflects how moral principles and standards can conflict when applied to contextually complex situations. To guide ethical judgment, it calls for a careful balancing of morally relevant considerations and an understanding of moral norms rather than categorical or absolute rules.

Keywords: clinical research; neuroscience; research ethics; placebo-controlled trials; active-controlled trials

Chapter.  9872 words. 

Subjects: Neuroscience

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