Modeling the Genomic Evolution of Gene Contents

Whole-genome analysis, e.g., the presence or absence of gene families over multiple genomes, is becoming an attractive approach for extracting the bulk phylogenetic signals and exploring the pattern of genome evolution. This chapter introduces several statistical models for this purpose. These include the likelihood function, the birth-death model with lateral gene transfer, the blocks model, the equal birth-death rate model; and the constant-birth, proportional-death model.

Whole-genome analysis, e.g., the presence or absence of gene families over multiple genomes, is becoming an attractive approach for extracting the bulk phylogenetic signals and exploring the pattern of genome evolution. This chapter introduces several statistical models for this purpose. These include the likelihood function, the birth-death model with lateral gene transfer, the blocks model, the equal birth-death rate model; and the constant-birth, proportional-death model.