Chapter

Country review: United States of America

Renslow Sherer

in A Decade of HAART

Published in print August 2008 | ISBN: 9780199225859
Published online September 2009 | e-ISBN: 9780191723834 | DOI: http://dx.doi.org/10.1093/acprof:oso/9780199225859.003.0010
Country review: United States of America

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This chapter considers selected aspects of the first decade of highly active antiretroviral therapy (HAART) in the United States. It begins with a review of the epidemiology and the scientific understanding of the pathogenesis of HIV disease in 1994. It then considers the societal impact of AIDS and the role of community activists, and turns to the state of treatment in 1994 and the early HAART era that followed, with emphasis on rapid access to treatment and early lessons with treatment adherence and toxicity. To better describe the impact of HAART at the local level, the chapter considers this era in Chicago with an emphasis on the public sector. It examines the issues that emerged in the early HAART era — particularly adherence, treatment toxicity, and drug resistance — that have greatly influenced trends in treatment outcomes. The chapter concludes with some observations for the coming decade of HIV/AIDS in the United States.

Keywords: highly active antiretroviral therapy; HAART; HIV/AIDS; epidemiology; treatment; Chicago; drug resistance

Chapter.  10568 words.  Illustrated.

Subjects: Public Health and Epidemiology

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