Economic evaluations of interventions for children in the developing world: The WHO-CHOICE approach

Tessa Tan-Torres Edejer, Moses Aikins, Robert Black, Lara Wolfson, Raymond Hutubessy and David B. Evans

in Economic Evaluation in Child Health

Published in print October 2009 | ISBN: 9780199547494
Published online February 2010 | e-ISBN: 9780191720055 | DOI:
 Economic evaluations of interventions for children in the developing world: The WHO-CHOICE approach

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There are logistical and analytical challenges when conducting economic evaluations in the developing world, ranging from lack of data on costs to determining generalizability. This chapter describes the WHO-CHOICE approach, a generalized form of cost-effectiveness analysis. By using the ‘null’ scenario which assumes an absence of interventions for treating or preventing a condition of interest, this method allows existing and new interventions to be analysed at the same time. Cost-effectiveness analysis for child health interventions are presented including oral rehydration therapy, case management for pneumonia, Vitamin A and zinc supplementation and fortification, provision of supplementary food during weaning with nutrition counseling, and measles vaccination using the WHO-CHOICE approach. Methods for costing interventions and assessing the population impact of the interventions are presented. Results are expressed in terms of cost per disability-adjusted life year (DALY) averted. The chapter concludes with a discussion of the value of the WHO-CHOICE approach to inform resource allocation.

Keywords: WHO-CHOICE; cost-effectiveness analysis; child health; vitamin supplementation; nutrition counseling; measles vaccination; disability-adjusted life year; DALY

Chapter.  5142 words.  Illustrated.

Subjects: Public Health and Epidemiology

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