Nutrition and cachexia

Josep M. Argilés, Sílvia Busquets, Mireia Olivan and Francisco J. López-Soriano

in Supportive Care in Respiratory Disease

Second edition

Published in print January 2012 | ISBN: 9780199591763
Published online May 2012 | e-ISBN: 9780191739149 | DOI:

Series: Supportive Care Series

Nutrition and cachexia

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Cachexia syndrome, characterized by a marked weight loss, anorexia, asthenia, and anaemia, leads to a malnutrition status due to the induction of anorexia or decreased food intake. In addition, metabolic disturbances (alterations in carbohydrate, lipid, and protein metabolism) lead to a decreased energy efficiency which accounts for weight loss. Muscle catabolism and wasting is one of the most prominent trends of the syndrome. Although the search for the cachectic factor(s) that triggers these metabolic alterations started a long time ago, and although many scientific and economic efforts have been devoted to its discovery, we are still a long way from knowing the whole truth. This chapter focuses on the role of nutrition in the treatment of cachexia, associated with both cancer and non-malignant respiratory diseases. The main aim is to summarize and evaluate the different approaches used in the past and to project trends for future nutritional interventions.

Keywords: cachexia syndrome; weight loss; anorexia; asthenia; anaemia; malnutrition

Chapter.  4857 words. 

Subjects: Palliative Medicine

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