Chapter

The neural synchrony model of tinnitus

Jos J. Eggermont

in The Neuroscience of Tinnitus

Published in print May 2012 | ISBN: 9780199605606
Published online September 2012 | e-ISBN: 9780191741555 | DOI: http://dx.doi.org/10.1093/acprof:oso/9780199605606.003.0009
The neural synchrony model of tinnitus

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In humans with tinnitus, changes in the synchrony between neural activity recorded with scalp electrodes are found. This suggests that large-scale cortical networks show higher synchrony in the gamma band and reduced synchrony in the alpha band. At the level of local circuits in cat auditory cortex increased spike firing synchrony is observed in conjunction with increased spontaneous firing rates. Such local synchrony could facilitate synchronous activity along fiber tracts connecting widely spaced cortical areas and hence result in more efficient information transfer. Tinnitus could thus be the consequence of the formation of a large-scale neural assembly in cortex that is especially pronounced during silence, but can be disrupted by external sound and may be modifiable by attention.

Keywords: burst firing; cross-correlation; central nervous system; micro and macro neural synchrony; epilepsy; kindling model; brain rhythms; neural networks

Chapter.  9482 words.  Illustrated.

Subjects: Neuroscience

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