Chapter

Tinnitus and aging

Jos J. Eggermont

in The Neuroscience of Tinnitus

Published in print May 2012 | ISBN: 9780199605606
Published online September 2012 | e-ISBN: 9780191741555 | DOI: http://dx.doi.org/10.1093/acprof:oso/9780199605606.003.0010
Tinnitus and aging

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Tinnitus prevalence increases with age. However, a comparison between findings following noise-induced hearing loss and age-related hearing loss suggests that aging may only play a minimal role in tinnitus. Nearly all changes in spontaneous firing rates are the result of peripheral hearing loss. That aging in itself does not induce tinnitus may have been glanced from the leveling off of the tinnitus prevalence for ages 〉65 year, i.e., when most people stop working and occupational noise effects do no longer play a role. The overall decrease in GABA and related inhibitory activity, which could induce or exacerbate tinnitus, appears to be compensated by other mechanisms.

Keywords: age-related hearing loss; noise-induced hearing loss; presbycusis; mouse model; genes; calcium channels; neurtransmitters; neuromodulators

Chapter.  10434 words.  Illustrated.

Subjects: Neuroscience

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