The Nature of Trials

Curtis L. Meinert

in An Insider’s Guide to Clinical Trials

Published in print May 2011 | ISBN: 9780199742967
Published online September 2011 | e-ISBN: 9780199897278 | DOI:
The Nature of Trials

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This chapter discusses the nature of clinical trials. The characterization of the nature of trials is based on published trials, as indexed in PubMed. But relying on published trials for insight into their nature is, in a way, akin to astronomers relying on light from stars to characterize what is in the universe. Obviously, by relying only on light that reaches the Earth, they have no way of knowing how many dead stars there are. Likewise, trialists looking at published trials have no way of knowing how many were done and not published and, like their fellow astronomers, are forced to rely on information coming to light years after they were born.

Keywords: clinical trial; published trials; PubMed; information

Chapter.  2774 words. 

Subjects: Medical Statistics and Methodology

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