Chapter

Biostatistics 101

Curtis L. Meinert

in An Insider’s Guide to Clinical Trials

Published in print May 2011 | ISBN: 9780199742967
Published online September 2011 | e-ISBN: 9780199897278 | DOI: http://dx.doi.org/10.1093/acprof:oso/9780199742967.003.0016
Biostatistics 101

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This chapter provides a refresher on biostatistics, specific to clinical trials, and a glossary of terms and definitions relevant to the analyses of clinical trials. The question, in the class of trials considered here (superiority, randomized phase III or IV trials with parallel-treatment designs), is whether the results are sufficient to conclude that the test treatment is superior to the comparison control treatment. The approach in addressing the question depends on the school of thought guiding the analysis, broadly: Bayesian, likelihood, and frequentist.

Keywords: clinical trial; biostatistics; statistical terms; test treatment

Chapter.  4747 words. 

Subjects: Medical Statistics and Methodology

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