Chapter

Implications of Total Energy Intake for Epidemiologic Analyses

Walter Willett

in Nutritional Epidemiology

Third edition

Published in print November 2012 | ISBN: 9780199754038
Published online January 2013 | e-ISBN: 9780199979448 | DOI: http://dx.doi.org/10.1093/acprof:oso/9780199754038.003.0011

Series: Monographs in Epidemiology and Biostatistics

Implications of Total Energy Intake for Epidemiologic Analyses

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Total energy intake deserves special consideration in nutritional epidemiology for three reasons: firstly, the level of energy intake may be a primary determinant of disease; secondly, individual differences in total energy intake produce variation in intake of specific nutrients unrelated to dietary composition because the consumption of most nutrients is positively correlated with total energy intake; and, thirdly, when energy intake is associated with risk of disease but is not a direct cause, associations with specific nutrients may be distorted (confounded) by total energy intake. Before examining these three issues in detail, this chapter discusses the physiologic aspects of energy utilization and the determinants of variation in energy intake in epidemiologic studies.

Keywords: nutritional epidemiology; nutrient intake; disease risk; energy utilization

Chapter.  15528 words.  Illustrated.

Subjects: Medical Statistics and Methodology

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