Chapter

Genetics of Late Life Involve Antagonistic Pleiotropy

Laurence D. Muller

in Does Aging Stop?

Published in print July 2011 | ISBN: 9780199754229
Published online September 2011 | e-ISBN: 9780199896714 | DOI: http://dx.doi.org/10.1093/acprof:oso/9780199754229.003.0005
Genetics of Late Life Involve Antagonistic Pleiotropy

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Reverse evolution experiments implicate antagonistic pleiotropy in the evolution of both mortality and fecundity during late life. Hybridization experiments do not implicate mutation accumulation in the evolution of late life, but do not necessarily preclude its involvement.

Keywords: reverse evolution; antagonistic pleiotropy; mutation accumulation; hybridization

Chapter.  4090 words.  Illustrated.

Subjects: Evolutionary Biology

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