Cellular Mechanisms of Memory: Complex Circuits

Howard Eichenbaum

in The Cognitive Neuroscience of Memory

Second edition

Published in print December 2011 | ISBN: 9780199778614
Published online May 2012 | e-ISBN: 9780199932962 | DOI:
Cellular Mechanisms of Memory: Complex Circuits

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This chapter reviews some of the progress toward a full characterization of one particular form of synaptic plasticity observed in the mammalian brain called long-term potentiation (LTP). LTP is only a laboratory phenomenon. Nevertheless, its mechanisms are now quite well understood, it can be induced in many brain structures that are involved in memory, and there is substantial evidence that the same cellular mechanisms that mediate LTP are required for lasting memory. The chapter reviews the state of our understanding of this important phenomenon as a likely candidate for memory coding in mammalian systems.

Keywords: synaptic plasticity; mammalian brain; long-term potentiation; memory coding

Chapter.  10451 words.  Illustrated.

Subjects: Neuroscience

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