Origins and early development of oligodendrocytes

William D. Richardson, Nigel P. Pringle, Wei-Ping Yu, Ellen J. Collarini and Anita Hall

in Glial Cell Development

Published in print November 1997 | ISBN: 9781872748542
Published online March 2012 | e-ISBN: 9780191724367 | DOI:

Series: The Molecular and Cellular Neurobiology Series

Origins and early development of oligodendrocytes

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This chapter begins with a discussion of the formation of the nervous system. It then describes oligodendrocyte precursors, migration of O-2A progenitors during normal development, oligodendrocyte precursors originate in a specialized region of the ventricular zone in the ventral half of the neural tube, oligodendrocyte development in the forebrain, specification of the oligodendrocyte lineage depends on signals from the ventral midline, and the embryonic origins of astrocytes.

Keywords: nervous system; neural tube; oligodendrocyte precursors; astrocytes

Chapter.  8305 words.  Illustrated.

Subjects: Neuroscience

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