Chapter

Transplantation of neuronal and nonneuronal cells into the brain

H. Widner

in Immune Responses in the Nervous System

Published in print November 1997 | ISBN: 9781872748795
Published online March 2012 | e-ISBN: 9780191724381 | DOI: http://dx.doi.org/10.1093/acprof:oso/9781872748795.003.0009

Series: Molecular and Cellular Neurobiology Series

Transplantation of neuronal and nonneuronal cells into the brain

Show Summary Details

Preview

Transplantation into the central nervous system has the potential to develop into a very powerful therapeutic approach for a variety of neurological disorders. This chapter discusses the principles of transplantation, the brain as transplantation site, transplantation of neural cells, potential therapies with intracerebral grafts, transplantation of nonneural cells, human trials with neural tissue transplants, immunological risks of transplantation, the use of immunosuppression, transplantation of transfected cells, and direct injection of oligonucleotides, virus vectors, and other noncellular approaches for gene transfer.

Keywords: central nervous system; neural cells; intracerebral grafts; neural tissue transplants; immunosuppression; transfected cells; oligonucleotides; virus vectors

Chapter.  17800 words.  Illustrated.

Subjects: Neuroscience

Full text: subscription required

How to subscribe Recommend to my Librarian

Buy this work at Oxford University Press »

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.