Journal Article

Physical Inactivity Is Associated with Lower Forced Expiratory Volume in 1 Second

Rupert W. Jakes, Nicholas E. Day, Bip Patel, Kay-Tee Khaw, Suzy Oakes, Robert Luben, Ailsa Welch, Sheila Bingham and Nicholas J. Wareham

in American Journal of Epidemiology

Published on behalf of Johns Hopkins Bloomberg School of Public Health

Volume 156, issue 2, pages 139-147
Published in print July 2002 | ISSN: 0002-9262
Published online July 2002 | e-ISSN: 1476-6256 | DOI:
Physical Inactivity Is Associated with Lower Forced Expiratory Volume in 1 Second

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Forced expiratory volume in 1 second (FEV1) is a strong risk factor for cardiovascular disease, stroke, lung cancer, and all-cause mortality. One possible explanation for this association is that FEV1 is a marker of other determinants of mortality risk, such as obesity and physical inactivity. In a population-based cohort study of 12,283 men and women aged 45–74 years from the European Prospective Investigation into Cancer-Norfolk Study recruited in 1993–1997, the cross-sectional association between physical activity and FEV1 and that between physical activity and change in FEV1 were analyzed. Indices of physical activity, including participation in vigorous recreational activity, stair climbing, and television viewing, were assessed with a validated questionnaire designed to assess activity in the previous year. Television viewing was negatively associated with FEV1 in men and women (p < 0.001), whereas stair climbing and participation in vigorous leisure time activities were positively associated with FEV1 in men and women (p < 0.001). The associations remained after adjustment for known confounders, including age, height, vitamin C, and smoking. Climbing more stairs and participating in vigorous leisure-time activity predicted a slower rate in annual percent decline in FEV1 (p < 0.004 and p < 0.002, respectively). In conclusion, physical activity is associated with higher levels of FEV1, whereas television viewing is associated with lower levels. Am J Epidemiol 2002;156:139–47.

Keywords: exercise; lung; television; Abbreviations: EPAQ2, European Prospective Investigation into Cancer Physical Activity Questionnaire; EPIC, European Prospective Investigation into Cancer; FEV1, forced expiratory volume in 1 second; MET, metabolic equivalent.

Journal Article.  4694 words.  Illustrated.

Subjects: Public Health and Epidemiology

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