Journal Article

Using Intake Biomarkers to Evaluate the Extent of Dietary Misreporting in a Large Sample of Adults: The OPEN Study

Amy F. Subar, Victor Kipnis, Richard P. Troiano, Douglas Midthune, Dale A. Schoeller, Sheila Bingham, Carolyn O. Sharbaugh, Jillian Trabulsi, Shirley Runswick, Rachel Ballard-Barbash, Joel Sunshine and Arthur Schatzkin

in American Journal of Epidemiology

Published on behalf of Johns Hopkins Bloomberg School of Public Health

Volume 158, issue 1, pages 1-13
Published in print July 2003 | ISSN: 0002-9262
Published online July 2003 | e-ISSN: 1476-6256 | DOI:
Using Intake Biomarkers to Evaluate the Extent of Dietary Misreporting in a Large Sample of Adults: The OPEN Study

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This paper describes the Observing Protein and Energy Nutrition (OPEN) Study, conducted from September 1999 to March 2000. The purpose of the study was to assess dietary measurement error using two self-reported dietary instruments—the food frequency questionnaire (FFQ) and the 24-hour dietary recall (24HR)—and unbiased biomarkers of energy and protein intakes: doubly labeled water and urinary nitrogen. Participants were 484 men and women aged 40–69 years from Montgomery County, Maryland. Nine percent of men and 7% of women were defined as underreporters of both energy and protein intake on 24HRs; for FFQs, the comparable values were 35% for men and 23% for women. On average, men underreported energy intake compared with total energy expenditure by 12–14% on 24HRs and 31–36% on FFQs and underreported protein intake compared with a protein biomarker by 11–12% on 24HRs and 30–34% on FFQs. Women underreported energy intake on 24HRs by 16–20% and on FFQs by 34–38% and underreported protein intake by 11–15% on 24HRs and 27–32% on FFQs. There was little underreporting of the percentage of energy from protein for men or women. These findings have important implications for nutritional epidemiology and dietary surveillance.

Keywords: biological markers; diet; diet surveys; energy intake; energy metabolism; epidemiologic methods; nutrition surveys; questionnaires; Abbreviations: DLW, doubly labeled water; FFQ, food frequency questionnaire; OPEN, Observing Protein and Energy Nutrition; PABA, para-aminobenzoic acid; 24HR, 24-hour dietary recall.

Journal Article.  7674 words.  Illustrated.

Subjects: Public Health and Epidemiology

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