Journal Article

A Population-based Study of the Prevalence of Abdominal Aortic Aneurysms in Relation to Bone Mineral Density

Lone Jørgensen, Kulbir Singh, Gro K. Rosvold Berntsen and Bjarne K. Jacobsen

in American Journal of Epidemiology

Published on behalf of Johns Hopkins Bloomberg School of Public Health

Volume 159, issue 10, pages 945-949
Published in print May 2004 | ISSN: 0002-9262
Published online May 2004 | e-ISSN: 1476-6256 | DOI: http://dx.doi.org/10.1093/aje/kwh132
A Population-based Study of the Prevalence of Abdominal Aortic Aneurysms in Relation to Bone Mineral Density

Show Summary Details

Preview

In a population-based study of 2,586 men and 2,806 postmenopausal women aged 55–74 years in Tromsø, Norway, in 1994–1995, associations between the prevalence of abdominal aortic aneurysms and bone mineral density were examined. The presence of an abdominal aortic aneurysm was assessed by ultrasonography. The bone mineral density of the forearm was measured by single X-ray absorptiometry. In postmenopausal women aged 55–64 years (nine cases of aneurysm), the adjusted odds ratio for abdominal aortic aneurysm was 0.42 (95% confidence interval: 0.19, 0.95) for each standard-deviation increase in bone mineral density. In other age groups (65–69 years and 70–74 years) including a total of 50 cases, the corresponding odds ratios for abdominal aortic aneurysm were 1.17 and 0.70, respectively. In men aged 55–59 years, based on 45 cases, the odds ratio for abdominal aortic aneurysm was 0.72 (95% confidence interval: 0.50, 1.03). In other age groups (60–64, 65–69, and 70–74 years) including a total of 206 cases, the odds ratios ranged from 1.00 to 1.10. The associations among men (in any age group) and among women older than 64 years were not statistically significant. The authors’ main conclusion is that abdominal aortic aneurysms and bone mineral density are not related. However, an association in younger subjects cannot be ruled out.

Keywords: aortic aneurysm, abdominal; bone density; Abbreviations: CI, confidence interval; SD, standard deviation.

Journal Article.  3367 words. 

Subjects: Public Health and Epidemiology

Full text: subscription required

How to subscribe Recommend to my Librarian

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.