Journal Article

BeoBLAST: distributed BLAST and PSI-BLAST on a Beowulf cluster

J. D. Grant, R. L. Dunbrack, F. J. Manion and M. F. Ochs

in Bioinformatics

Volume 18, issue 5, pages 765-766
Published in print May 2002 | ISSN: 1367-4803
Published online May 2002 | e-ISSN: 1460-2059 | DOI:
BeoBLAST: distributed BLAST and PSI-BLAST on a Beowulf cluster

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Summary: BeoBLAST is an integrated software package that handles user requests and distributes BLAST and PSI-BLAST searches to nodes of a Beowulf cluster, thus providing a simple way to implement a scalable BLAST system on top of relatively inexpensive computer clusters. Additionally, BeoBLAST offers a number of novel search features through it's web interface, including the ability to perform simultaneous searches of multiple databases with multiple queries, and the ability to start a search using the PSSM generated from a previous PSI-BLAST search on a different database. The underlying system can also handle automated querying for high throughput work.

Availability: Source code is available under the GNU public license at



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Subjects: Bioinformatics and Computational Biology

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