Journal Article

ITFP: an integrated platform of mammalian transcription factors

Guangyong Zheng, Kang Tu, Qing Yang, Yun Xiong, Chaochun Wei, Lu Xie, Yangyong Zhu and Yixue Li

in Bioinformatics

Volume 24, issue 20, pages 2416-2417
Published in print October 2008 | ISSN: 1367-4803
Published online August 2008 | e-ISSN: 1460-2059 | DOI: http://dx.doi.org/10.1093/bioinformatics/btn439
ITFP: an integrated platform of mammalian transcription factors

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Summary: Investigation of transcription factors (TFs) and their downstream regulated genes (targets) is a significant issue in post-genome era, which can provide a brand new vision for some vital biological process. However, information of TFs and their targets in mammalian is far from sufficient. Here, we developed an integrated TF platform (ITFP), which included abundant TFs and their targets of mammalian. In current release, ITFP includes 4105 putative TFs and 69 496 potential TF-target pairs for human, 3134 putative TFs and 37 040 potential TF-target pairs for mouse, and 1114 putative TFs and 18 055 potential TF-target pairs for rat. In short, ITFP will serve as an important resource for the research community of transcription and provide strong support for regulatory network study.

Availability: ITFP can be accessed at http://itfp.biosino.org/itfp

Contact: yyzhu@fudan.edu.cn; yxli@sibs.ac.cn

Journal Article.  1316 words. 

Subjects: Bioinformatics and Computational Biology

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