Journal Article

BEST: Bayesian estimation of species trees under the coalescent model

Liang Liu

in Bioinformatics

Volume 24, issue 21, pages 2542-2543
Published in print November 2008 | ISSN: 1367-4803
Published online September 2008 | e-ISSN: 1460-2059 | DOI: http://dx.doi.org/10.1093/bioinformatics/btn484
BEST: Bayesian estimation of species trees under the coalescent model

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Summary: BEST implements a Bayesian hierarchical model to jointly estimate gene trees and the species tree from multilocus sequences. It provides a new option for estimating species phylogenies within the popular Bayesian phylogenetic program MrBayes. The technique of simulated annealing is adopted along with Metropolis coupling as performed in MrBayes to improve the convergence rate of the Markov Chain Monte Carlo algorithm.

Availability: http://www.stat.osu.edu/~dkp/BEST.

Contact: lliu@oeb.harvard.edu

Journal Article.  1422 words.  Illustrated.

Subjects: Bioinformatics and Computational Biology

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